Best Practices In Adherence Monitoring: A Case Study Of Philadelphia Fight

Monday, June 29th 2020

10:00 AM - 11:30 AM


We have access to a biomedical intervention called pre-exposure prophylaxis (PrEP) which can reduce the risk of HIV seroconversion by 99% when taken daily. However, non-adherence to PrEP is an ever-present concern. This workshop will explore the utilization of urine tenofovir testing for PrEP adherence monitoring at Philadelphia FIGHT from the perspectives of both providers and patients. We will be presenting national data on the use of tenofovir adherence monitoring and will present preliminary findings around changes in adherence over time, the ability of non-adherence to predict non-retention, and demographic differences in non-adherence. We will then shift to a real-world perspective of this technology and hear from a provider at Philadelphia FIGHT who has utilized this test. This provider will offer best practices and lessons learned around the use of this technology in a clinical setting. We will also discuss doing adherence counselling virtually (over the phone or via telehealth) and how to navigate those types of experiences.


  1. Educating participants on the national implications of adherence monitoring and the preliminary data on its implementation to date
  2. Offering participants best practices on the implementation of this technology and its utility in a clinical setting.


Shane Hebel, JD

UrSure Inc.

Shane Hebel is the Director of Product for UrSure., which makes diagnostic tests aimed at monitoring and improving medication adherence. Shane leads the company’s research and development and clinical validation teams. He is also a member of the Boston HIV Research Community Advisory Board. Prior to UrSure, Shane worked at McKinsey, where he focused on payor and regulatory healthcare clients, and UNAIDS, where he worked in HIV law and policy.





Harlan Shaw

Philadelphia FIGHT

Harlan Shaw is currently the PrEP Coordinator at Philadelphia Fight’s YHEP Health Center where he works with the adolescents’ population ages 13-24 providing PrEP& PEP resources, linkage to medical care, assisting with financial coverage for those who are uninsured. He has 10+ years working with youth and in the HIV /STI prevention field as a HIV tester and counselor, life skills specialist and case manager. Harlan aims connect individuals in the tristate area to Philadelphia FIGHT’s PrEP program as well as develop innovative approaches to assist patient with PrEP Adherence.

Location Details


Spotlight On

Karam Mounzer, MD

Dr. Mounzer identified two major gaps in the care of patients with HIV/hepatitis C (HCV) co-infection, and the complexity of multidrug-resistant HIV treatment. He is involved with many clinical trials focusing on drug development and better understanding of HIV immunopathogenesis with the Wistar Institute. He is involved in teaching and mentoring.

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Dr. Karam Mounzer

Dr. Mario Cruz

Dr. Mario CruzDr. Cruz is a board certified pediatrician who serves as the Medical Director for our Pediatrics and Adolescent Health Center. He has presented and/or published in the fields of community violence and domestic violence prevention, quality improvement, behavioral health, curriculum development and mentorship. In 2019 he received the Greater Philadelphia Social Innovation Award for Innovations in Healthcare.

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